使用呼吸道和接触预防措施来减少SARS-CoV-2感染的传播与子宫内膜炎-羊内膜感染的减少无关
Jacqueline Roig1,2, Chelsea A DeBolt1, Mariela Cabrera1
1Department of Obstetrics, Gynecology, and Reproductive Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
American journal of perinatology
|April 24, 2024
概括
流行性感染控制预防措施,包括掩护和患者限制,并没有显著改变子宫内膜炎/胎内感染 (IAI) 的风险. 该研究发现,这些新协议与COVID-19大流行期间IAI的发生率之间没有关联.
科学领域:
- 产科和妇科 产科和妇科
- 传染病控制和控制传染病
- 公共卫生 公共卫生
背景情况:
- 由于COVID-19大流行,医疗机构需要加强感染控制措施,包括产科服务.
- 这些措施涉及患者和医疗保健工作人员严格的协议,以减轻SARS-CoV-2的传播.
- 这些预防措施对其他产科并发症,如子宫内膜炎/胎内感染 (IAI) 的潜在影响需要调查.
研究的目的:
- 评估COVID-19大流行期间实施额外的接触和呼吸预防措施是否影响了产科服务中的子宫内膜炎/胎内感染 (IAI) 的发生率.
- 为了比较流行病时期和历史流行病前时期之间的IAI率.
主要方法:
- 进行了一项单一中心的历史队列研究,将大流行期间 (2020年3月至5月) 的分娩与大流行前期间 (2019年3月至5月) 的分娩进行了比较.
- 数据是从电子医疗记录中提取的.
- 用逆治疗权重概率 (IPTW) 的逻辑回归来调整潜在的混因素,并比较两个时期之间的子宫内膜炎/IAI风险.
主要成果:
- 子宫内膜炎/IAI的发病率在大流行期间 (4.0%) 和大流行前期间 (5.1%) 之间相似,没有统计学上显著的差异 (p=0.15).
- 与大流行前组相比,在大流行期间分娩的患者的体重指数 (BMI) 较高,并接受了较少的数字宫检查.
- 在使用IPTW进行风险因素调整后,分娩时间与子宫内膜炎/IAI无关 (OR=0.76,95% CI [0.52,1.11]).
结论:
- 实施的SARS-CoV-2接触和呼吸道预防措施与子宫内膜炎/胚胎内感染 (IAI) 风险的变化无关.
- 疫情初期的几个月,数字宫检查减少,产后母亲的BMI增加.
- 这些发现表明,严格的病毒性呼吸道疾病感染控制措施可以在产科环境中实施,而不会对常见的细菌产后感染率产生不利影响,如子宫内膜炎/IAI.
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