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Updated: Jun 28, 2025

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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一个新的模拟介质系统用于体外评估生物等效肠道药物溶解度

Qamar Abuhassan1, Maria Inês Silva2, Rana Abu-Rajab Tamimi2

  • 1Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, United Kingdom; Department of Pharmaceutics and Pharmaceutical Technology, School of Pharmacy, University of Jordan, Amman 11942, Jordan.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
|April 24, 2024
PubMed
概括

一个新的九媒体系统准确地模拟了快食和食状态的肠液溶解度. 这种体外法改善了药物溶解性预测,有助于制药开发.

关键词:
在平衡状态下,溶解度是平衡的.禁食了 禁食了 禁食了美国联邦储备局 Fed Fed Fed人的肠液是人类的肠液.IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC在体外和体内相关的相关性模拟肠道液体的模拟

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