精神病症状,相关的药理疗法和认知功能:一项基于男性人口的研究
Kayla B Corney1, Amanda L Stuart1, Julie A Pasco2
1Deakin University, IMPACT - Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Geelong, Victoria, Australia.
Journal of affective disorders
|April 24, 2024
概括
抑郁症状和抗药物使用与男性认知功能较差有关. 对这些关联的进一步研究可以帮助理解认知衰老,并为预防策略提供信息.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 老年学是一门学科.
背景情况:
- 精神疾病及其治疗可能会影响认知功能.
- 对于整个成年年龄段,基于人口的数据有限.
- 这项研究的重点是一般人群中的男性.
研究的目的:
- 检查精神病症状和心理药物使用与男性认知功能之间的关系.
- 识别潜在的可修改的认知衰退风险因素.
主要方法:
- 在吉隆骨质疏松症研究中利用了537名男性的数据.
- 使用Cog-State简要电池评估认知功能 (精神运动功能,注意力,工作记忆,视觉学习).
- 通过医院焦虑和抑郁量表测量抑郁和焦虑症状;心理药物使用是自我报告的. 采用了线性回归模型.
主要成果:
- 抑郁症状与较低的整体认知功能,精神运动功能和注意力相关.
- 心理药物使用与整体认知功能和注意力降低有关.
- 抗药的使用与整体认知功能,注意力和工作记忆的降低有显著的关联.
- 焦虑症状,抗抑郁药和抗焦虑药的使用没有显示出与认知领域的显著关联.
结论:
- 抑郁症状和抗药的使用与男性认知功能下降有关.
- 了解这些关联背后的机制对于推进对认知衰老的知识至关重要.
- 这些发现可能会为未来的认知衰退预防计划提供信息.
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