门诊全关节和膝关节整形手术的口服术后抗生素预防:描述当前的做法
Avanish Yendluri1, Jiwoo Park1, Priya Singh1
1Leni and Peter W. May Department of Orthopaedics, Icahn School of Medicine at Mount Sinai, New York, New York.
The Journal of arthroplasty
|April 24, 2024
概括
只有16.5%的门诊全关节整形手术 (THA) 和全膝关节整形手术 (TKA) 患者接受了口服抗生素预防. 抗生素的选择和处方率因患者因素,手术类型和位置而异,表明需要标准化指南.
科学领域:
- 整形外科手术 整形外科手术
- 预防传染病 预防传染病
- 医疗保健服务研究 医疗服务研究
背景情况:
- 门诊全关节整形术 (THA) 和全膝关节整形术 (TKA) 越来越常见.
- 对这些程序的抗生素预防处方实践的大规模数据有限.
研究的目的:
- 描述口服抗生素预防的国家实践,在门诊处方THA和TKA.
- 为了确定与接受抗生素预防相关的因素.
主要方法:
- 全国回顾性队列研究 (2018-2021) 使用国家索赔数据库.
- 包括18-64岁患者的初级门诊THA/TKA.
- 提取和分类术后口服抗生素处方;使用后勤回归来分析关联.
主要成果:
- 在73,015例门诊THA/TKA手术中,口服抗生素预防在16.5%被处方.
- 类药物是最常见的 (74.3%),其次是克林达米辛,硫甲醇-trimethoprim 和多克西环素.
- 在患有肥胖/糖尿病/自身免疫疾病的患者中,以及在门诊外科手术中心的手术中,THA与TKA的预防几率更高.
结论:
- 术后口服抗生素预防在门诊THA/TKA中未得到充分利用,处方方面存在显著差异.
- 人口,临床和程序因素影响了预防接收.
- 需要进一步的研究来评估预防对减少感染风险的影响.
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