慢性肺炎和健康对照组之间的步行差异:系统性审查和元分析
Joren Buekers1,2,3, Laura Delgado-Ortiz4,2,3, Dimitrios Megaritis5
1ISGlobal, Barcelona, Spain joren.buekers@isglobal.org.
概括
患有慢性阻塞性肺病 (COPD) 的人比健康人走得更慢,可能会增加他们跌倒的风险. 需要进一步的研究来了解COPD中的步行障碍.
科学领域:
- 肺部医学 肺部医学
- 老年病的医生 老年病的医生
- 生物力学 生物力学
背景情况:
- 步态对于老年人的移动性,独立性和生存至关重要.
- 步行障碍被认为是导致跌倒,残疾和死亡的重要危险因素.
- 了解慢性阻塞性肺病 (COPD) 中的步态变化是有限但至关重要的.
研究的目的:
- 在监督步行测试期间,系统地审查和识别步行特征的差异.
- 为了比较COPD患者和健康对照人群之间的步态参数.
主要方法:
- 在11个电子数据库中进行了全面的系统文献搜索,并补充了谷歌学者和手动参考检查.
- 数据选,提取和质量评估由两个审查员独立进行.
- 进行了对被认为没有高偏差风险的研究的元分析.
主要成果:
- 该审查包括25项研究,包括1015名COPD患者和2229名健康对照.
- 低质量的证据表明,COPD患者的步行速度明显低于通常的对照者 (MD -19 cm·s−1) 和快速的速度 (MD -30 cm·s−1).
- 在其他步行特征 (如步骤长度,持续时间,节奏或宽度) 中没有发现统计学意义上的变化.
结论:
- 与健康个体相比,COPD患者的步行速度较慢,这表明可能有助于增加跌倒风险.
- 关于COPD中特定的空间和时间步态组件变化的证据仍然没有确定性.
- 步行障碍是COPD管理的一个关键,但研究不足的方面.
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