德克萨斯州的COVID-19临床试验参与和意识
Justin M Luningham1, Idara N Akpan1, Sarah Alkhatib1
1Department of Population & Community Health, School of Public Health, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX, USA.
Human vaccines & immunotherapeutics
|April 24, 2024
概括
德克萨斯州对COVID-19临床试验的认识很低,由于安全问题和不信任,许多人犹不决地注册. 增加社区教育对于促进参与疫苗和治疗研究至关重要.
科学领域:
- 公共卫生 公共卫生
- 临床研究 临床研究
- 流行病学 流行病学
背景情况:
- 由于COVID-19的流行,疫苗和治疗方法的快速开发成为必要.
- 由于错误信息和普遍的犹,临床试验招生面临挑战.
- 代表性招生对于评估预防措施至关重要.
研究的目的:
- 评估对德克萨斯州COVID-19疫苗和治疗临床试验的认识,参与意愿和招生情况.
- 确定影响参与临床试验的因素.
- 了解参加COVID-19临床试验的障碍.
主要方法:
- 在2022年6月至7月期间,在线调查了1089名德克萨斯州居民的配额样本.
- 受访者报告了对COVID-19临床试验的认识,参与意愿和实际招生情况.
- 分析了数据,以确定参与试验的人口和态度预测因素.
主要成果:
- 45.8%的德克萨斯人知道COVID-19临床试验,但只有13.2%的人报名参加.
- 高等教育与更高的意识和入学率相关.
- 与男性和年轻人相比,女性和老年人 (55岁以上) 的意愿和入学率不同.
- 关键障碍包括安全问题,政府的不信任以及对试验流程的不确定性.
结论:
- 德克萨斯州的COVID-19临床试验意识和招生存在重大差距.
- 解决错误信息和建立社区信任对于未来的试验招聘至关重要.
- 需要有针对性的宣传和教育,以提高参与率,并确保代表性的研究人群.
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