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在小鼠前带带皮上,平衡跨膜抑制减轻了视觉空间疏忽

Kerstin Erika Schmidt¹

¹Neurobiology of Vision Lab, Brain Institute, Federal University of Rio Grande do Norte, Natal, Brazil; Göttingen Campus Institute for Dynamics of Biological Networks, Georg-August University, Göttingen, Germany.

Trends in neurosciences

|April 24, 2024

概括

研究人员在小鼠前带膜皮层 (ACC) 中发现了一个跨膜抑制电路. 这个电路平衡大脑半球的视觉空间注意力,并调节视觉皮层活动.

科学领域:

神经科学是一个神经科学.
大脑皮层研究研究大脑皮层研究
半球间通信半球间通信

背景情况:

前环皮质 (ACC) 在认知功能中起着至关重要的作用.
了解半球间通信对于大脑功能至关重要.
大脑皮层内的抑制电路是神经处理的关键.

研究的目的:

为了识别和描述小鼠ACC中的特定的跨管抑制电路.
阐明这个电路在调节大脑半球之间的神经活动中的作用.
为了确定电路对视觉空间注意力和视觉皮层调制的贡献.

主要方法:

电生理学记录在小鼠的ACC.
电路追踪技术用于识别神经元连接.
在体内实验中评估行为和神经调制.

主要成果:

在小鼠ACC.中发现了一种新型的跨管抑制电路.
这个电路激发相反侧面的帕瓦胺阳性 (PV+) 内神经元.
该电路被证明可以调节双侧激发音和对侧抑制.

结论:

已识别的ACC电路对于维持半球间平衡至关重要.
这个电路介导视觉空间注意力.
它提供视觉皮层的自上而下的调制,影响视觉处理.

关键词:

前带带状动物前带带状动物关注注意力注意力注意力注意力身体的质体 (callosum) 是一个体.半球间的连接是半球之间的连接.动物动物动物视觉视觉视觉视觉视觉是一个

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