患有子宫内膜异位症的女性缺铁风险:基于人口的前性队列研究
Dereje G Gete1, Jenny Doust1, Sally Mortlock2
1Australian Women and Girls' Health Research Centre, School of Public Health, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
概括
患有子宫内膜异位症的女性面临更高的铁缺乏症风险. 铁缺乏症的早期发现和治疗与子宫内膜异位症护理一起至关重要.
科学领域:
- 生殖健康 生殖健康
- 血液学 血液学 血液学
- 慢性疾病流行病学 慢性疾病流行病学
背景情况:
- 子宫内膜异位症可能通过炎症或大量月经出血与铁缺乏有关.
- 之前的研究缺乏关于子宫内膜异位症与缺铁关系的纵向数据.
研究的目的:
- 调查子宫内膜异位症与患铁缺乏症的风险之间的纵向关联.
主要方法:
- 利用了来自澳大利亚妇女健康纵向研究 (2000-2018年) 3,294名妇女的数据.
- 通过自我报告的调查和验证的行政健康记录,确定了子宫内膜异位症和铁缺乏症的诊断.
- 采用了通用估计方程来分析七个时间点之间的关联.
主要成果:
- 患有子宫内膜异位症的女性表现出明显更高的缺铁风险 (aOR=1.46,95% CI [1.29,1.66]).
- 经过手术确认和临床怀疑的子宫内膜异位症病例都显示出铁缺乏症风险增加.
- 在考虑到大量月经出血后,这种关联略有减少 (8%).
结论:
- 子宫内膜异位症的诊断与铁缺乏症的风险增加有关.
- 在被诊断为子宫内膜异位症和持续护理期间,建议同时治疗铁缺乏症.
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