需要达成一致的慢性脱水的定义:一个范围审查
Yoko Hasegawa1, Katsunori Kato2, Kazuhiro Ogai1
1Department of Bio-engineering Nursing, Graduate School of Nursing, Ishikawa Prefectural Nursing University, Ishikawa, Japan.
Drug discoveries & therapeutics
|April 24, 2024
概括
慢性脱水,在老年人中经常被忽视,缺乏明确的定义. 这份综述强调了各种定义,并呼吁达成国际共识,以改善认可和临床结果.
科学领域:
- 老年学是一门学科.
- 临床医学 临床医学
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 脱水在老年人中很普遍,显著影响临床结果.
- 慢性脱水是未被认可的,这构成了临床挑战.
研究的目的:
- 系统地审查和总结慢性脱水现有的定义.
- 确定当前定义中的差距,并提出未来的研究方向.
主要方法:
- 进行了对四个数据库 (PubMed,CINAHL,Cochrane Library,Science Direct) 的系统范围审查.
- 包含了从开始到2023年6月8日定义慢性脱水的同行评审文章.
- 两个研究人员独立审查文章,通过讨论解决分歧.
主要成果:
- 确定了五篇文章,涵盖了各种年龄组的定义.
- 确定的定义包括血尿素升高,由于流体流失而体重减轻>1%,血尿素与肌素比率>20,血清度≥295mOsm/kg,或持续≥72小时的脱水.
- 在不同研究中,慢性脱水的定义存在显著差异.
结论:
- 目前对慢性脱水的定义是不一致和多样化的.
- 有必要就慢性脱水的定义建立国际共识.
- 标准化定义对于改善慢性脱水的识别,诊断和管理至关重要,特别是在老年人中.
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