相互关联的环境挑战:重金属与药物相互作用及其对生态系统的影响
S Madesh1, Gokul Sudhakaran2, Ramu Meenatchi1
1Toxicology and Pharmacology Laboratory, Department of Biotechnology, Faculty of Science and Humanities, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, India.
Drug and chemical toxicology
|April 24, 2024
概括
工业污染释放重金属和制药废物,形成危险的金属药物复合物 (MDC). 这些MDC比单个污染物带来更大的生态风险,影响整个生态系统的水生生物和植被.
科学领域:
- 环境科学 环境科学
- 生态毒理学 生态毒理学
- 环境化学环境化学
背景情况:
- 工业扩张和环境安全措施不足导致了广泛的污染.
- 重金属 (HM) 和制药废物是主要的环境污染物,对水生物种和植被产生重大影响.
- 现有的研究往往忽视了多种污染物的综合作用及其复杂的相互作用.
研究的目的:
- 审查人类活动产生的HM的环境来源和排放途径.
- 研究HM和药物物质之间的相互作用,导致金属药物复合体 (MDC) 的形成.
- 突出不同生态系统中同时出现的污染物和MDCs所带来的累积风险.
主要方法:
- 文献综述,重点关注HMs的环境来源和排放途径.
- 对HM和制药化合物之间的相互作用进行分析.
- 检查不同生态系统中MDC形成机制.
- 评估污染物和MDCs的同时存在和生物积累.
主要成果:
- 重金属和制药废物在大气,土壤和水资源中普遍存在.
- 人体药物和药物之间的相互作用导致金属药物复合物 (MDC) 的形成.
- 这些MDC被纳入生物体的食物层,造成显著的生态风险.
- MDCs的综合风险大于单个污染物的风险.
结论:
- 人类活动是HM和制药废物的重要来源,导致环境污染.
- 形成MDC是一个复杂的环境挑战,有可能破坏生态系统的相互依赖.
- 解决同时出现的污染物和MDCs的累积影响对于有效的环境风险评估和管理至关重要.
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