饮食,肠道菌群和功能性胃肠道疾病之间的关系:证据,怀疑和前景
Tianxu Liu1,2, Ismail Muhammad Asif1,2, Yan Chen1,2
1College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, 430070, China.
Molecular nutrition & food research
|April 25, 2024
概括
肠道真菌或mycobiome影响肠道健康. 本综述探讨了饮食如何影响肠道真菌及其在功能性胃肠道疾病 (FGIDs) 中的作用,表明地中海饮食可能有利于FGID患者.
科学领域:
- 微生物学和真菌学:专注于肠道真菌生物组.
- 胃肠病学:研究功能性胃肠道疾病 (FGIDs).
- 营养科学:饮食在调节肠道微生物群中的作用.
背景情况:
- 肠道真菌是肠道微生物生态系统的组成部分.
- 饮食模式显著影响真菌生物组的组成和功能.
- 虽然肠道菌群在胃肠道疾病中的作用正在出现,但其与FGIDs的特定联系仍未得到充分探索.
研究的目的:
- 审查饮食营养素和模式对肠道菌群的影响.
- 探索肠道真菌在FGIDs病变发生过程中的潜在参与.
- 根据真菌生物组调制,确定针对FGIDs的潜在饮食干预措施.
主要方法:
- 文献综述综合了关于肠道真菌,饮食和FGIDs的当前研究.
- 分析了将真菌生物组变化与FGID发展联系在一起的拟议机制.
- 评估饮食模式,特别是地中海饮食,用于FGID管理.
主要成果:
- 饮食因素可以改变肠道真菌种群和整体真菌生物组结构.
- 肠道真菌可能通过免疫调节,内共生或与肠道细菌的相互作用来促进FGID的发病.
- 地中海饮食显示出作为FGID患者合适的饮食模式的承诺.
结论:
- 肠道真菌在FGID的发病过程中发挥着作用,受饮食习惯的影响.
- 了解肠道真菌生物组为FGID治疗策略提供了新的途径.
- 通过饮食干预来准真菌生物组,如地中海饮食,可能会减轻FGID症状.
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