在Angus料场牛群中,对牛呼吸系统疾病耐药性的基因组估计育种值
Ben J Hayes1, Christian J Duff2, Bradley C Hine3
1Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, QLD 4072, Australia.
Journal of animal science
|April 25, 2024
概括
基因组选择可以帮助养殖牛对牛呼吸系统疾病 (BRD) 具有抵抗力. 这项研究发现,对BRD耐药性的基因组预测是中度准确的,这表明在养区的基因改进潜力.
科学领域:
- 动物遗传学动物遗传学
- 畜牧业生产 畜牧业生产
- 兽医科学 兽医科学 兽医科学
背景情况:
- 牛呼吸道疾病 (BRD) 在全球料场牛行业造成了重大经济损失.
- 之前的研究表明,牛中BRD耐药性的遗传基础,遗传性估计表明选择的潜力.
- 基因组选择为改善BRD耐药性提供了一个有希望的策略,特别是当疾病表型在繁殖动物中不易获得时.
研究的目的:
- 导出和评估基因组估计育种值 (GEBVs) 的准确性,以检测养场牛的BRD耐药性.
- 评估基因组选择在牛肉生产系统中增强BRD耐药性的潜力.
主要方法:
- 利用了来自两个养区的1213只安格斯牛的数据集,记录了BRD治疗数据.
- 采用贝叶斯R方法来推导BRD抗性的GEBV.
- 进行了五次交叉验证,以评估基因组预测的准确性.
主要成果:
- 使用贝叶斯R方法,对BRD耐药性的基因组预测显示了中等准确性 (0.23 ± 0.01).
- 结果验证了使用基因组信息来选择具有改善BRD耐药性的牛的可行性.
结论:
- 基因组选择是一种可行的工具,可以提高养场牛的牛呼吸系统疾病耐药性.
- 建议对更大,更多样化的群体进行进一步的研究,以优化GEBV的开发,以便广泛的工业应用.
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