在韩国,稳定慢性阻塞性肺病患者的不适当的峰值吸气流率
Seong Hwan Youn1, Hyun Jung Kim1, Jae Seok Park1
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea.
Tuberculosis and respiratory diseases
|April 25, 2024
概括
许多患有慢性阻塞性肺病 (COPD) 的患者使用吸入器是不正确的. 这项研究发现,42.1%的干粉吸入器用户和17.2%的气溶设备用户具有不适当的峰值吸入流量 (PIFR).
科学领域:
- 肺部医学 肺部医学
- 呼吸系统疗法 呼吸系统疗法
背景情况:
- 吸入疗法对于治疗慢性阻塞性肺病 (COPD) 至关重要.
- 峰值吸入流量 (PIFR) 显著影响吸入治疗的疗效.
- 在韩国COPD患者中低于最佳PIFR的患病率以前没有研究过.
研究的目的:
- 确定韩国COPD患者中不适当的PIFR的患病率.
- 调查非最佳PIFR和COPD评估测试 (CAT) 分数之间的相关性.
- 为了确定与COPD患者不充分的PIFR相关的因素.
主要方法:
- 108名COPD患者使用相同的吸入器超过一年而没有恶化.
- 测量PIFR使用一个在检查 DIAL G16 灵感流量计.
- 不适当的PIFR被定义为干粉吸入器 (DPI) 的<60 L/min和气溶设备的>90 L/min.
主要成果:
- 观察到不适当的PIFR的高患病率:42.1%的DPI用户和17.2%的气溶设备用户.
- 与适当的PIFR (7.5±4.9) 患者相比,不适当的PIFR患者的CAT得分显著更高 (11.2±7.7).
- 在DPI使用者中,女性性别,较低的身高,较低的体重和减少的最大自愿通风 (MVV) 与不适当的PIFR有关.
结论:
- 该研究强调了韩国COPD患者中低于最佳PIFR的显著流行,特别是在DPI使用者中.
- 低于最佳的PIFR与更糟糕的症状负担有关,由更高的CAT得分表明.
- 女性性别,身高较低,体重较低和MVP降低等因素与DPI用户的PIFR不足有关,这表明可能需要针对性的干预措施.
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