是增加的干部曲站起来与肌肉软弱或避免疼痛与单边膝盖疼痛的个体相关;一个模拟研究研究
Eline Van Der Kruk1, Thomas Geijtenbeek1,2
1Department of Biomechanical Engineering, Faculty of Mechanical Engineering, Delft University of Technology, Delft, Netherlands.
Frontiers in bioengineering and biotechnology
|April 25, 2024
概括
在膝关节骨关节炎患者的Timed Up and Go测试期间,干部曲的增加很可能源于肌肉疲弱,而不是避免疼痛. 预测模拟显示肌肉容量减少,而不是避免疼痛,导致这种常见的步态补偿策略.
科学领域:
- 生物力学 生物力学
- 神经肌肉生理学 神经肌肉生理学
- 临床评估 临床评估
背景情况:
- 定时启动和移动 (TUG) 测试是步态和平衡评估的标准临床工具.
- 在膝关节骨关节炎 (KOA) 中观察到 TUG 期间干屈曲的增加,但其原因 (肌肉疲软与疼痛避免) 尚不清楚.
- 区分运动补偿的潜在原因对于有效治疗至关重要.
研究的目的:
- 为了区分肌肉疲软和避免疼痛,因为这些因素有助于在坐到走动过程中增加干部曲.
- 利用预测性神经肌肉模拟来建模这些促成因素.
主要方法:
- 使用预测性神经肌肉建模模拟的坐走动作.
- 通过减少巨大的肌肉同度力 (20-60%) 来建模肌肉疲弱.
- 通过设置峰值膝盖负荷值 (2-4倍体重) 来模拟疼痛避免.
主要成果:
- 肌肉容量下降 (模拟的软弱) 导致干曲的增加.
- 避免疼痛的模拟导致较慢的速度和改变的肌肉招募,但没有增加干部曲.
- 模拟表明,干部曲主要与肌肉疲弱有关.
结论:
- 预测模拟表明,KOA中干部曲的增加更多地表明肌肉软弱,而不是避免疼痛.
- 研究结果支持肌肉衰弱对晚期KOA的影响,与动力学和肌肉激活差异保持一致.
- 这些见解可以指导针对KOA运动变化的更有针对性的治疗干预措施.
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