弥合差距:在阿尔茨海默氏症和老年人群中多民族人群中的老年人对照中对脑组织的多奥米克分析
Joseph S Reddy1, Laura Heath2, Abby Vander Linden2
1Mayo Clinic Florida, 4500 San Pablo Rd S, Jacksonville, FL 32224.
bioRxiv : the preprint server for biology
|April 25, 2024
概括
这项研究扩展了阿尔茨海默氏症 (AD) 多组数据,包括非洲裔美国人和拉丁美洲人. 这一基础数据集将有助于发现与AD影响的所有人群相关的精准医学目标.
科学领域:
- 神经科学是一个神经科学.
- 基因组学就是基因组学.
- 蛋白质组学是指蛋白质组学.
背景情况:
- 阿尔茨海默病 (AD) 多组组研究已经确定了潜在的治疗点,但缺乏多样性.
- 非洲裔美国人 (AA) 和拉丁裔美国人 (LA) 不成比例地受到AD的影响,突出了包容性研究的需要.
结论:
- 在多学科研究中包括代表性不足的群体对于确定全面的精准医学目标至关重要.
- 这种包容性的方法确保治疗发现有利于所有受阿尔茨海默病影响的人群.
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