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Updated: Jun 28, 2025

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
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Published on: August 17, 2022

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在大麻素受体1的活性和非活性状态下,形态动态的差异性行为

Ugochi H Isu, Adithya Polasa, Mahmoud Moradi

    bioRxiv : the preprint server for biology
    |April 25, 2024
    PubMed
    概括

    非活性大麻素受体1 (CB1) 比其活性状态更灵活,跨膜螺旋体7在这种动态差异中发挥着关键作用. 这一发现有助于理解CB1激活和药物发现.

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