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Updated: Jun 28, 2025

Detergent-free Ultrafast Reconstitution of Membrane Proteins into Lipid Bilayers Using Fusogenic Complementary-charged Proteoliposomes.
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Detergent-free Ultrafast Reconstitution of Membrane Proteins into Lipid Bilayers Using Fusogenic Complementary-charged Proteoliposomes.

Published on: April 5, 2018

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蛋白质-脂质预融合复合体的动态形成

Maria Bykhovskaia1

  • 1Department of Neurology, Wayne State University, Detroit MI 48201.

bioRxiv : the preprint server for biology
|April 25, 2024
PubMed
概括

突触囊泡融合是由Synaptotagmin 1 (Syt1) 和Complexin (Cpx) 介导的. 分子动力学模拟显示,Syt1-Cpx相互作用对于Ca2+触发的聚变至关重要,形成了聚变前的复合体或非生产性的死胡同状态.

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