一项研究表明,在患有肺癌的患者中,用户更喜欢适应的REQUITE患者报告结果问卷,而不是PRO-CTCAE®
Thomas Jordan1,2,3, Thitikorn Nuamek2, Isabella Fornacon-Wood1,2
1Division of Cancer Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, United Kingdom.
Frontiers in oncology
|April 25, 2024
概括
调整后的REQUITE问卷显示出与临床医生的评估更好的一致性,肺癌患者更喜欢它而不是PRO-CTCAE®. 推REQUITE用于肺癌护理的常规临床使用.
科学领域:
- 在瘤学瘤学.
- 患者报告的结果
背景情况:
- 患者报告的结果 (PROs) 提高了症状收集的准确性,存活率和生活质量.
- 对比PRO工具对于优化癌症护理至关重要.
研究的目的:
- 为了比较共同的术语标准对不良事件 (PRO-CTCAE®) 的患者报告结果版本和适应的REQUITE肺问卷之间的一致性和患者偏好.
- 评估这些PRO工具在肺癌患者中的适用性.
主要方法:
- 肺癌患者填写了PRO-CTCAE®和调整的REQUITE问卷.
- 临床医生报告的结果使用CTCAE v4.03.03进行评估.
- 使用皮尔森相关系数和顺序逻辑回归来测量一致性.
主要成果:
- 在PRO工具和临床医生报告的结果之间发现了很高的一致性 (Pearson的r:0.66-0.91,p <.001).
- 与PRO-CTCAE®相比,调整后的REQUITE问卷显示出与临床医生报告的结果有更好的相关性.
- 54%的患者更喜欢调整后的REQUITE问卷,因为它清晰易用.
结论:
- 调整后的REQUITE问卷提供了与临床医生评估的更好的一致性,以及患者在肺癌治疗中的更高的偏好.
- 推使用REQUITE作为常规临床实施,用于治疗肺癌患者.
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