多发性硬化症患者运动的影响:系统性审查和元分析
Liwen Du1,2, Haoyu Xi1,2, Shiyan Zhang2
1Key Laboratory of Physical Fitness and Exercise, Ministry of Education, Beijing Sport University, Beijing, China.
Frontiers in public health
|April 25, 2024
概括
运动显著改善了多发性硬化症 (MS) 患者的平衡,行走能力,耐力,疲劳和生活质量. 阻力和有氧运动对分别疲劳和生活质量是最有效的,年轻人看到更大的疲劳改善.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 运动科学 运动科学
背景情况:
- 关于运动对多发性硬化症 (MS) 的影响,存在相互矛盾的发现.
- 本元分析综合了有关MS患者运动干预措施的证据.
- 专注于关键的结果:平衡,行走,耐力,疲劳和生活质量.
研究的目的:
- 系统地评估运动对MS患者的平衡,行走能力,行走耐力,疲劳和生活质量的影响.
- 确定最有效的运动方式,以改善MS患者的特定结果.
- 探索影响运动有效性的因素,如参与者的年龄.
主要方法:
- 在PubMed,Web of Science,Scopus和Cochrane数据库中进行系统的文献搜索,截至2024年3月1日.
- 包括随机对照试验 (RCT),重点关注MS患者的运动干预措施.
- 对40项研究 (1300名练习参与者) 的元分析,以计算各种结果措施的加权平均差异和置信区间.
主要成果:
- 运动显著改善了MS患者的平衡 (BBS),行走能力 (TUG),行走耐力 (6MWT),疲劳水平和生活质量 (MSQOL-54).
- 耐力运动在疲劳方面表现出最大的改善,而有氧运动对生活质量最有效.
- 亚组分析表明,年轻的年龄与疲劳的更大改善有关.
结论:
- 运动为MS患者的平衡,步行,耐力,疲劳和生活质量提供了显著的好处.
- 耐力训练在减少疲劳方面表现出色,而有氧运动可以提高生活质量.
- 年龄是一个因素,年轻的多发性硬化症患者经历了运动带来的更大的疲劳改善.
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