评估抗生素治疗指南在第三级护理环境中对持续抗生素管理的遵守:一项回顾性观察性研究
Suman Pant1,2, Andrew Corwin2, Prabhat Adhikari3
1Government of Nepal, Nepal Health Research Council, Kathmandu, Nepal.
概括
尼泊尔医生对抗生素指南的遵守率很低,在常见感染中为37.9%. 需要采取干预措施来改善抗生素处方模式,并打击抗菌素耐药性.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 抗菌素耐药性 (AMR) 构成了全球健康的重大威胁.
- 抗生素治疗指南对于适当的处方和AMR制至关重要.
- 医生遵守这些指导方针是必不可少的,但往往不够理想.
研究的目的:
- 评估医生遵守尼泊尔医院抗生素治疗指南.
- 确定与遵守常见感染抗生素指南相关的因素.
主要方法:
- 一个回顾性,单心的观察性研究审查了成年住院患者的医疗记录.
- 2018年1月至2019年12月的数据包括尿路感染 (UTI),肺炎或皮肤和软组织感染 (SSTI) 的患者.
- 评估了对抗生素处方指南建议的遵守情况.
主要成果:
- 在符合条件的患者中,抗生素指南的总体遵守率为37.9%.
- 坚持率因感染而异:尿路感染为37.9%,肺炎为43.3%,SSTI为26.4%.
- 处方塞夫特里亚克松 (OR=2.09) 或勒沃素 (OR=4.63) 与显著更高的坚持相关.
结论:
- 在尼泊尔的第三级护理中心观察到,抗生素指南的遵守率很低.
- 尽管有最新的指导方针,但当前的抗生素处方模式需要紧急关注.
- 需要量身定制的干预措施来改善指导方针的遵守和减轻AMR.
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