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在被诊断为十二指甲状腺癌的患者中,远程转移的风险因素,预后因素和名录:基于人口的研究研究

Jia-Rong Shang¹, Chen-Yi Xu^1,2, Xiao-Xue Zhai¹

¹Department of Oncology, Jiangsu Province Hospital of Chinese Medicine, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210000, Jiangsu Province, China.

World journal of gastrointestinal oncology

|April 25, 2024

概括

这项研究开发了两种名图,用于预测十二指腺癌患者的远程转移 (DM) 风险和预后. 这些工具可以帮助临床决策,以获得更好的患者结果.

科学领域:

在瘤学瘤学.
医学统计医学统计
癌症研究癌症研究

背景情况:

十二指肠癌是一种小肠癌亚型,预后不佳,患有远程转移 (DM).
现有的名谱缺乏DM诊断和预后评估初级十二指肠癌的重点.

研究的目的:

开发和验证用于预测十二指肠癌中DM风险的诺米克图.
为DM的十二指腺癌患者创建个性化预后评估的诺姆图.

主要方法:

利用监测,流行病学和最终结果数据库 (2010-2019) 来获取十二指腺癌患者数据.
采用后勤和考克斯回归分析来确定风险和预后因素.
通过使用ROC,校准和DCA曲线验证的诺米克表现.

主要成果:

确定性别,等级,瘤大小,T阶段和N阶段作为独立的DM风险因素.
确定年龄,组织学,T阶段,等级,大小,骨转移,化疗和手术作为DM的预后因素.
诺米图表在预测多个数据集中的DM发生和预后方面表现出高准确度.

结论:

两种新的诺米图有效预测十二指甲状腺癌中远程转移的风险.
这些名图提供了个性化的预后预测,增强了十二指腺癌患者的临床决策.

关键词:

遥远的转移遥远的转移十二指甲腺癌是什么意思这个名字叫做Nomogram.预测因素预测因素风险因素风险因素

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