胆道腺癌的临床和社会经济生存决定因素
Laura Sahyoun1, Kay Chen2,3, Cynthia Tsay4
1Department of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, NY 10065, United States. las4024@med.cornell.edu.
World journal of gastrointestinal oncology
|April 25, 2024
概括
更高的收入和教育水平与胆道癌症的更高的存活率有关. 较低的社会经济地位,特别是在低收入县,与这些恶性瘤的较差结果有关.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 胆道癌 (BTC) 尽管治疗进展,但存活率很低.
- 关于社会经济地位 (SES),种族/种族和环境因素对BTC生存的影响的数据有限.
研究的目的:
- 调查社会经济地位和种族/种族与胆管和胆囊腺癌的生存结果之间的关联.
主要方法:
- 利用了来自监测,流行病学和最终结果 (SEER) 数据库 (1975-2016) 的数据.
- 分析了社会经济因素,包括收入,教育,贫困,吸烟和城市人口百分比.
- 采用Cox的比例危险模型来评估5年生存率.
主要成果:
- 包括15,883例胆囊病例,11,466例肝内病例,12,869例肝外胆道病例和7,268例父腺癌.
- 较高的县收入,大学教育水平和城市人口百分比与改善的5年生存率有关 (HRs在0.96-0.97,P<0.05之间).
结论:
- 较低收入县的胆道癌症的生存结果较差.
- 更高的收入和教育水平与改善胆囊和胆道恶性瘤的5年整体存活率相关.
更多相关视频
12:24A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
5.2K
07:32Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis
Published on: April 12, 2024
1.3K
相关概念视频
Cancer Survival Analysis
345
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
345
Actuarial Approach
77
The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
77
