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Updated: Jun 27, 2025

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在光滑肌肉细胞表型转换中的lncRNA-miRNA-mRNA相互作用的整合性分析

Aatish Mahajan1, Junyoung Hong1, Irene Krukovets1

  • 1Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States.

Frontiers in genetics
|April 25, 2024
PubMed
概括

在光滑肌细胞 (SMC) 中的多能性因子OCT4调节长非编码RNA (lncRNA) 和microRNA (miRNA),影响动脉样硬化中的细胞迁移和细胞化. 这项研究揭示了SMC表型转变中的新型OCT4依赖机制.

关键词:
在 OCT4 激活过程中,综合性分析是一种综合性分析.长长的非编码RNAs.微型RNAs是一种微型RNA.顺肌细胞是平滑肌肉的细胞.

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