相关实验视频

Updated: Jun 16, 2026

An Inexpensive Adaptation of a Commercial Microwave Reactor for Solid Phase Peptide Synthesis
06:17

An Inexpensive Adaptation of a Commercial Microwave Reactor for Solid Phase Peptide Synthesis

Published on: November 22, 2024

388

优化合成时间和可持续性,使用新型环保二元溶剂系统,在自动化合成器上进行感应加热

Lorenzo Pacini1,2, Manoj Muthyala3, Luisa Aguiar3

  • 1Interdepartmental Research Unit of Peptide and Protein Chemistry and Biology - Peptlab, MoD&LS Laboratory, University of Florence, Sesto Fiorentino, Italy.

Journal of peptide science : an official publication of the European Peptide Society
|April 25, 2024
PubMed
概括

新规定限制N,N-二甲基形式胺 (DMF) 在固相合成 (SPPS). 这项研究探讨了更安全,更绿色的溶剂替代品,发现基于二甲基硫氧化物的混合物有效合成具有挑战性的序列.

关键词:
二元混合物溶剂的二元混合物基于捕获和释放的净化.难以合成的类合成.绿色的合成合成.绿色的溶剂 绿色的溶剂感应加热辅助的合成.固相合成固相合成

更多相关视频

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation11:09

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

10.7K
Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation08:48

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation

Published on: January 26, 2016

11.8K

相关概念视频

Production of Pharmaceuticals01:30

Production of Pharmaceuticals

Industrial insulin production uses genetically engineered E. coli expressing a proinsulin gene controlled by a tryptophan promoter and containing a methionine linker for later cleavage. The cells also carry ampicillin resistance for selective growth. Seed cultures are stored at −80 °C and production begins by thawing a small amount to inoculate starter cultures, which are progressively scaled to a 50,000-L bioreactor. In the bioreactor, E. coli grow in nutrient-rich media under sterile, tightly...