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Updated: Jun 27, 2025

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SPTLC3对于复合I活动至关重要,并有助于缺血性心肌病

Anna Kovilakath1, Adolfo G Mauro2, Yolander A Valentine3,4

  • 1Department of Human and Molecular Genetics (A.K., M.J., J.J.W., M.A.S.), Virginia Commonwealth University, Richmond.

Circulation
|April 25, 2024
PubMed
概括

在缺血性心肌病中诱导血清棕转移酶3 (SPTLC3),产生不典型的脂物,损害心脏功能. 通过增强线粒体综合体I活性,减少SPTLC3可以改善心脏功能和存活率.

关键词:
心肌疾病电子运输复合物I线粒体氨酸C-棕甲基转移酶甲状腺脂类

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