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Updated: Jun 27, 2025

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[Elesclomol-Cu诱导人体急性髓性白血病细胞中的质亡]

Yan-Hua Yu1,2, Huan-Juan Li2, Xin-Yi Yang1,2

  • 1The Second Clinical Medical School of Zhejiang Chinese Medical University， Hangzhou 310053, Zhejiang Province, China.

Zhongguo shi yan xue ye xue za zhi
|April 25, 2024
PubMed
概括

埃莱斯克洛莫尔-Cu (ES-Cu) 有效地抑制人类急性髓性白血病 (AML) 细胞增殖,并通过增加反应性氧物种 (ROS) 和减少谷氨 (GSH) 来诱导cuproptosis. 这表明ES-Cu是潜在的新型AML治疗剂.

关键词:
急性髓性白血病; 埃尔斯克洛莫尔-Cu; 型亡.

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