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[来自C57BL/6J小鼠的CD19化学抗原受体T细胞的构建和优化]

Chun-Xiao Ren1,2, Li Zhao1,2, Xian-Xian Chen1,2

  • 1Blood Disease Institute, Xuzhou Medical University, Xuzhou 221000, Jiangsu Province, China.

Zhongguo shi yan xue ye xue za zhi
|April 25, 2024
PubMed
概括

优化C57BL/6J小鼠的化学抗原受体T细胞 (CAR-T) 治疗需要特定的刺激. 将抗CD3/CD28涂层与IL-2相结合,可以获得最高的mCD19 CAR-T细胞感染效率.

关键词:
C57BL/6J小鼠;CD19;仿真抗原受体T细胞

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