[前列腺癌 - - 一种正在转变的疾病]
1professor, överläkare, Prostatacancercentrum, Sahlgrenska universitetssjukhuset, Göteborg.
Lakartidningen
|April 25, 2024
概括
前列腺癌 (前列腺特异抗原) 查和治疗方面的进展使85岁以下男性的死亡率下降了一半. 改进的诊断方法减少了过度诊断,通过国家注册表加强了患者护理和研究.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
背景情况:
- 20世纪90年代,前列腺特异性抗原 (PSA) 测试和前列腺活检的引入导致局部前列腺癌的诊断和激进治疗的增加.
- 诊断方法的显著进步和对瘤生物学的更深入的理解对于完善前列腺癌护理至关重要.
研究的目的:
- 提供当代前列腺癌护理的概述,强调关键进展及其影响.
- 讨论前列腺癌管理中的诊断和治疗策略的演变.
- 强调国家注册和患者组织在改善前列腺癌结果方面的作用.
主要方法:
- 审查当代的前列腺癌护理实践和进展.
- 分析新诊断工具和治疗方法对患者治疗结果的影响.
- 检查瑞典国家前列腺癌登记册 (NPCR) 的作用和演变.
主要成果:
- 在引入PSA检测和活检后,局部前列腺癌和激进治疗的发生率显著增加.
- 改进的诊断和对瘤生物学的理解现在正在缓解过度诊断,并使有组织的查成为可能.
- 由于更有效的治疗方法和早期诊断,85岁以下男性的前列腺癌年龄标准化死亡率已减少一半.
结论:
- 当代前列腺癌的治疗得到了显著的改善,导致死亡率降低.
- 有组织的查,先进的诊断和有效的治疗是改善患者结果的关键.
- 像NPCR这样的国家注册表对于支持临床护理和研究至关重要,与患者组织日益增长的影响力一起.
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