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Updated: Jun 27, 2025

Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen
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Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen

Published on: May 30, 2012

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克罗辛通过减少BIRC5表达来增强人类乳腺癌细胞对帕克利塔塞尔的敏感性

Yunhao Jia1, Han Yang2, Jinsong Yu3,4

  • 1Department of General Surgery, Nanyang First People's Hospital Affiliated to Henan University, Nanyang, China.

Chemical biology & drug design
|April 25, 2024
PubMed
概括

克罗辛是一种沙夫兰化合物,通过减少BIRC5表达,克服PTX耐药性和改善患者生存结果,增强了对乳腺癌的帕克利塔塞尔 (PTX) 疗效.

关键词:
在BIRC5中,有5个问题.灭症 (apoptosis) 是一种死亡的过程.乳腺癌 乳腺癌 乳腺癌克罗辛克罗辛克罗辛克罗辛克罗辛克克罗辛克罗辛克克罗辛克帕克利塔克塞尔耐药性已经出现.

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