通过实时组织弹性学在手术前和手术前的化疗和放射治疗后评估阳门功能
Akira Sakamoto1, Kazuhito Sasaki2, Hiroaki Nozawa2
1Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan. sakamotoa-sur@h.u-tokyo.ac.jp.
International journal of colorectal disease
|April 25, 2024
概括
化学辐射疗法可能会导致内部关节硬化,导致弹性降低和潜在的直肠功能障碍. 这可能表现为更高的静止压力和恶化Wexner分数在直肠癌患者.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 手术瘤学手术瘤学
背景情况:
- 化学放射治疗是直肠癌的标准治疗方法.
- 化学辐射疗法可能会影响直肠功能.
- 治疗后内部关节弹性变化尚不清楚.
研究的目的:
- 为了研究化学放射治疗后内部关节弹性的变化和直肠功能之间的关系.
- 通过通过门的超声波和实时组织弹性图形来量化内部门关节硬度.
主要方法:
- 对27名直肠癌患者进行前性队列研究.
- 透过门的超声波与实时组织弹性学,以测量化学放射治疗前后的内部门关节弹性.
- 评估了弹性变化,最大静止压力,最大挤压压力和韦克斯纳分数之间的相关性.
主要成果:
- 59.3%的患者表现出化学辐射疗法后弹性 (硬化) 降低.
- 内部关节硬化组的最大静止压力显著更高 (63.0 mmHg与47.0 mmHg).
- 在硬化症小组中,韦克斯纳评分的恶化更为常见 (60.0%对18.2%).
结论:
- 化学辐射疗法诱导的内部关节硬化可能与直肠功能障碍有关.
- 降低弹性与增加的最大静止压力相关.
- 需要进一步的研究才能充分了解对直肠功能的影响.
更多相关视频
15:49Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
31.8K
09:01Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice
Published on: March 10, 2015
10.0K
相关概念视频
01:25Assessment of the Rectum and Anus
205
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
205
01:26Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
83
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
83