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使用AGREE II仪器系统评估默克尔细胞癌临床实践指南
Deepak Lakshmipathy1, Christian Fritz1, Jacob Harris2
1Department of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania, 800 Walnut Street, 18th Floor, Philadelphia, PA, 19107, USA.
Archives of dermatological research
|April 25, 2024
概括
这项研究使用AGREE II工具评估了默克尔细胞癌 (MCC) 临床实践指南 (CPG). 两个CPG是高质量的,但大多数缺乏利益相关者的投入和开发严格性.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 临床指南开发 临床指南开发
背景情况:
- 默克尔细胞癌 (MCC) 是一种罕见的,激进的皮肤癌,需要多学科的护理.
- 标准化管理算法对于最佳的患者治疗结果至关重要.
- 临床实践指南 (CPG) 旨在规范MCC治疗方法.
研究的目的:
- 批判性地评估现有的默克尔细胞癌 (MCC) 临床实践指南 (CPG).
- 通过研究和评估指南的评估 (AGREE II) 工具评估MCC CPG的质量和发展严格性.
主要方法:
- 使用系统审查和元分析 (PRISMA) 标准的优先报告项目进行系统的文献搜索,确定了八个MCC CPG.
- 四名受过培训的评估人员使用AGREE II工具评估了CPG.
- 类内相关系数 (ICCs) 评估了审查员的一致性.
主要成果:
- 在八个MCC CPG中,有两个被评为高质量;五个是中等质量的,一个是低质量的.
- 欧洲皮肤病论坛/欧洲皮肤瘤学协会/欧洲癌症研究和治疗组织 (EDF/EADO/EORTC) 的CPG得分最高.
- 大多数CPG都缺乏有关利益相关者参与,适用性和开发严格性的细节.
结论:
- 虽然一些MCC CPG表现出良好的发展质量,但许多需要改进.
- 未来的MCC CPG开发应该纳入公众观点,外部专家审查和实施考虑.
- 在AGREE II工具中,评估指南的制定质量,而不是建议的有效性.
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