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相关概念视频

Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

127
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
127
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

145
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
145
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

331
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
331
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF01:24

Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF

134
Tumor Necrosis Factor (TNF), a proinflammatory cytokine, contributes significantly to the inflammation seen in Crohn's disease. It exists as soluble TNF and membrane-bound TNF, with actions mediated through TNF receptors (TNFR). TNFR activation leads to the release of proinflammatory cytokines, T-cell activation, collagen production, and leukocyte migration, all contributing to inflammation in Crohn's disease. Anti-TNF monoclonal antibodies, namely infliximab (Remicade), adalimumab...
134
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

222
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
222
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

172
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
172

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Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells
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干预性炎症性肠病:当前和未来的实践

Benjamin Clement1, Juan Reyes Genere2

  • 1Department of Digestive Diseases, University of Cincinnati, Cincinnati, Ohio.

Current opinion in gastroenterology
|April 25, 2024
PubMed
概括

对于炎症性肠道疾病 (IBD) 的内镜干预正在推进,为形和狭窄等并发症提供最少的侵入性选择. 为了深入了解克罗恩病的表现,需要进一步的研究.

科学领域:

  • 胃肠病学 胃肠病学
  • 最少侵入性的手术
  • 内镜治疗药物 内镜治疗药物

背景情况:

  • 炎症性肠病 (IBD) 呈现出显著的瘤和结构性并发症.
  • 患病率上升和治疗挑战需要先进的管理策略.
  • 内镜的进步为IBD并发症的手术提供了最小入侵的替代方案.

研究的目的:

  • 审查内镜干预在治疗IBD中的当前和未来应用.
  • 突出内镜在解决IBD相关并发症方面的不断变化的作用.

主要方法:

  • 审查目前用于IBD管理的内镜技术.
  • 分析新兴的内镜技术及其潜在应用.
  • 对内镜切除,严格切除和支架的证据的评估.

主要成果:

  • 内镜切除主要用于结肠炎相关的发育不良.
  • 越来越多的证据证明了内镜下膜剖析;修改后的技术需要更多的研究.
  • 纤维肌性疾病的内镜方法 (严格切除,支架,扩张) 变得越来越清晰.
  • 目前正在研究透性和术后IBD并发症的内镜治疗.

结论:

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  • 对于IBD的内镜治疗方法,特别是对于发育不良和狭窄症,正在变得越来越精细.
  • 仍然存在重大知识差距,特别是在透性IBD表现方面.
  • 内镜为管理近门和透性克罗恩病提供了有前途的未来机会.