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在Roux-en-Y胃绕道术后营养结果的变化:系统性审查和元分析
Leizhen Duan1, Yan Wang2, Lingling Cheng3
1Department of Medical Services, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, China.
Obesity surgery
|April 25, 2024
概括
鲁克斯-en-Y胃绕道手术 (RYGB) 影响营养状况,降低维生素A,费里丁和水平. 虽然一些营养素,如维生素D和B12增加,整体营养后果是不利的.
科学领域:
- 腹腔外科手术是什么意思
- 营养科学 营养科学
- 代谢健康 代谢健康
背景情况:
- 减肥手术 (BS) 对严重肥胖有效,并改善血糖控制.
- 在BS之后的营养结果,特别是Roux-en-Y胃绕道 (RYGB),仍然存在争议.
- 评估RYGB后的微量营养素变化对于患者管理至关重要.
研究的目的:
- 综合评估RYGB对各种营养结果的影响.
- 综合现有证据,对关键维生素,矿物质和相关标记在RYGB之后的变化.
主要方法:
- 在多个数据库 (PubMed,Embase,Web of Science,Cochrane,WanFang,CNKI) 进行了系统的文献搜索.
- 评估了关键的营养参数,包括维生素A,25-氧维生素D [25(OH) D],,,偏激素 (PTH),铁,费里丁,维生素B12,叶酸和.
- 数据使用随机效应模型进行聚合,将结果表达为标准平均差异 (SMD) 与95%置信区间 (CI).
主要成果:
- 包括5645名参与者参与的56个研究.
- 在RYGB后观察到25 ((OH) D,,PTH,维生素B12和叶酸水平的显著增加.
- 相反,血清费里,维生素A和血水平的显著下降.
结论:
- RYGB导致多个营养标记物的显著变化.
- 尽管增加了一些有益的营养素,但RYGB的整体营养影响包括关键维生素和矿物质的不利变化.
- 在RYGB.之后,对营养状况的监测和管理至关重要.
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