糖尿病患者的非糖尿病病:发病率,HbA1c变异性和其他预测因素,以及影响
Bülent Demirelli1, Burcu Boztepe2, Elif Gülcan Şenol2
1Department of Nephrology, Marmara Unıversity Pendik Training and Research Hospital, Nephrology Clinic, Fevzi Çakmak Quarter Muhsin Yazıcıoğlu Street No: 10 Üst Kaynarca, Pendik, İstanbul, Turkey. bulentdemirelli@hotmail.com.
非糖尿病性病 (NDNP) 影响了一半患有慢性病 (CKD) 的糖尿病患者. 关键预测因素包括女性性别,糖尿病视网膜病变的不存在,以及积极的免疫学标记,指导脏活检决策.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 糖尿病学 糖尿病学
- 病理学 病理学 病理学
背景情况:
- 糖尿病是慢性病 (CKD) 的主要原因.
- 非糖尿病病 (NDNP) 发生在很大比例的糖尿病患者中,影响预后和治疗.
- 临床判断通常用于确定糖尿病患者需要活检 (KB) 的必要性.
研究的目的:
- 调查糖尿病患者中NDNP的发生率.
- 确定用于预测NDNP的实验室和临床指标.
- 了解NDNP与糖尿病进展之间的关系.
主要方法:
- 76名接受脏活检 (KB) 的糖尿病患者的回顾性分析.
- 根据活检结果,患者被分为糖尿病病 (DNP) 或非糖尿病病 (NDNP) 组.
- 使用HbA1c测量的平均值,平均值和标准偏差来定义HbA1c的变化.
主要成果:
- 在研究的糖尿病患者中,NDNP被诊断为50%.
- 常见的NDNP类型包括焦点细分型淋巴细胞硬化症 (FSGS),膜性淋巴细胞炎和IgA炎.
- 预测NDNP的因素包括女性性别,没有糖尿病视网膜病变,糖尿病持续时间较短,蛋白尿,血尿,白血尿,阳性免疫标志物和非HbA1c可变性.
结论:
- 许多患有CKD的糖尿病患者患有NDNP,因此需要准确的诊断才能进行适当的治疗.
- 预测NDNP的预测因素包括糖尿病视网膜病变的不存在,非HbA1c的变异性,女性性别和阳性免疫检测.
- 这些因素可以帮助临床医生决定糖尿病患者的活检,并在未来的研究中进一步调查.
更多相关视频
07:22Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
Published on: March 7, 2025
04:36Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
Published on: January 12, 2024
相关概念视频
Diabetes: Symptoms, Diagnosis, and Complications
Diabetes Mellitus: Type 2 and Gestational
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
