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无法吐综合征:胃肠科医生需要知道的内容
André Smout1, Albert J Bredenoord, Renske Oude Nijhuis
1Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, the Netherlands.
Current opinion in gastroenterology
|April 25, 2024
概括
无法吐综合征,其特点是胸痛和胀气,源于上食道关节无法放松. 诊断往往依赖于自我评估和症状学,肉毒素注射显示出有希望.
科学领域:
- 胃肠病学 胃肠病学
- 食道运动障碍 食道运动障碍
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 无法吐综合征是一种以无法释放吞的空气为特征的疾病.
- 症状包括胸部疼痛,胀气和过度膨胀,通常从幼儿时期开始.
研究的目的:
- 审查最近关于无法发综合征的出版物.
- 了解这种疾病的发病,诊断和治疗.
主要方法:
- 五个回顾性病例系列的综合征无法排泄的综合征的审查.
- 一项机理学研究的分析,涉及八名患有这种疾病的患者.
- 检查上食道关节 (UES) 功能在病变发生中的作用.
主要成果:
- 无法吐综合征通常在儿童早期表现为胸痛,胀气和声等症状.
- 患者经常根据在线信息进行自我诊断.
- 在食道膨胀期间,UES缺乏反射性放松是其发展的关键因素.
- 毒素注射到喉肌肉中显示出良好的反应,有助于诊断.
结论:
- 无法吐综合征是一种由UES功能障碍引起的已知的疾病.
- 过度诊断是一个问题,因为仅仅依赖症状.
- 需要进行进一步的严格研究,包括双盲安慰剂对照试验,以确认肉毒素治疗的疗效.
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