肠道微生物群的多样性从肉的和缩综合征通过metagenomics执行的肠道微生物群多样性
Dayse Helena Lages da Silva1, Rodrigo Luiz Marques da Silva1, Diego Lisboa Rios2
1Pathology Sector and MULTILAB, Department of Veterinary Clinic and Surgery, Veterinary School, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
Avian pathology : journal of the W.V.P.A
|April 25, 2024
概括
在家禽中,慢性发育不良综合征 (RSS) 破坏了肠道健康,改变了乳腺微生物群的组成. 这种病毒性疾病减少了微生物的多样性和丰富性,影响了的健康.
科学领域:
- 禽畜科学 禽畜科学 禽畜科学
- 微生物学 微生物学
- 动物卫生 动物健康
背景情况:
- 发育不良和发育不良综合征 (RSS) 是一种影响商业家禽的肠道病毒性疾病,主要影响肠道健康.
- RSS对肉小肠道微生物群组成的特定影响在很大程度上仍未被描述.
研究的目的:
- 为了研究自然受到RSS影响的肉小的状细菌群体中的组成变化.
- 使用下一代测序来比较RSS受影响和健康小之间的肠道微生物群.
主要方法:
- 从7天大的肉幼 (11个有RSS,10个健康的) 中分析了阴茎含量和粘膜.
- 利用下一代测序 (NGS) 技术来分析细菌群落.
- 样品来源于巴西米纳斯吉拉斯州的一个商业农场.
主要成果:
- RSS显著改变了肠道微生物群,减少了受影响小的微生物丰富性和多样性.
- 在接受RSS的小中,观察到 *Lactobacillus* 丰度的显著下降.
- 增加 *Candidatus Arthromitus* 和 *Clostridium sensu stricto 1* 的流行率与 RSS 有关.
结论:
- 病毒感染 (RSS) 和肉小的肠道微生物失调症之间存在直接关系.
- 肠道微生物组合的变化可能会导致RSS的炎症和疾病病原体.
- 特定的细菌种群,如 *Candidatus Arthromitus* 和 *Clostridium sensu stricto 1*,是RSS的潜在指标.
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