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Updated: Jun 27, 2025

A Chromatin Immunoprecipitation Assay to Identify Novel NFAT2 Target Genes in Chronic Lymphocytic Leukemia
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TRAF3功能丧失揭示了非正规的NF-κB通路作为扩散大B细胞淋巴瘤的治疗点

Michael Y Li1,2, Lauren C Chong1, Gerben Duns1

  • 1Centre for Lymphoid Cancer, British Columbia Cancer, Vancouver, BC V5Z 1L3, Canada.

Proceedings of the National Academy of Sciences of the United States of America
|April 25, 2024
PubMed
概括

在扩散性大B细胞淋巴瘤 (DLBCL) 中,TRAF3基因的反复删除激活非正规NF-κB通路. 准NIK,一个关键酶,显示出治疗TRAF3缺乏DLBCL的希望.

关键词:
功能模型的功能模型.淋巴瘤淋巴瘤是什么身体突变 - 身体突变有针对性的治疗方法.瘤微环境是一个微环境.

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