缺血性中风患者的2型糖尿病 - 一项全国性的研究
Sidsel Hastrup1, Jakob Nebeling Hedegaard2, Grethe Andersen1,3
1Danish Stroke Centre, Neurology, Aarhus University Hospital, Aarhus, Denmark.
概括
在缺血性中风 (IS) 患者中,2型糖尿病 (T2D) 的患病率从2004年至2020年增加. 虽然死亡率下降,但T2D患者的死亡率仍然较高,这凸显了改善护理策略的需要.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 2型糖尿病 (T2D) 是缺血性中风 (IS) 的重要危险因素,导致患者的治疗结果较差.
- 脑卒中和糖尿病管理都取得了进展,需要对它们的相互作用有更新的理解.
研究的目的:
- 调查IS患者T2D的患病率和趋势.
- 分析风险因素,药物使用,护理质量和T2D和无T2DIS患者的临床结果的变化.
- 评估中风严重程度,住院,死亡率,再入院和复发性中风率的时间趋势.
主要方法:
- 基于注册表的队列研究使用了2004年至2020年期间丹麦的所有IS事件进行.
- 患有T2D的IS患者与没有糖尿病的患者进行了比较.
- 对年龄,性别,中风严重程度,并发症和社会经济因素进行调整的分析.
主要成果:
- 在IS患者中T2D的患病率在2004-2006年和2019-2020年之间从12.0%上升到17.0%.
- 调整后的30天死亡风险在IS与T2D下降,但仍然较高 (9.9%至7.8%).
- 患有T2D的IS患者始终经历了更高的30天和365天死亡率和再入院率.
结论:
- 在缺血性中风患者中,T2D的发病率随着时间的推移而增加.
- 尽管情况有所改善,但IS患者患有并发性T2D的死亡率和再入院率仍然很高.
- 迫切需要加强策略,以改善患有2型糖尿病的缺血性中风患者的预后.
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