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Updated: Jun 26, 2026

Rapid and Efficient Zebrafish Genotyping Using PCR with High-resolution Melt Analysis
06:30

Rapid and Efficient Zebrafish Genotyping Using PCR with High-resolution Melt Analysis

Published on: February 5, 2014

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一个仪器,客观的微卫星不稳定性分析,使用高分辨率的融分析.

Kamilla Kolding Bendixen1, Sofie Forsberg-Pho1, Giulia Dazio2

  • 1PentaBase A/S, Odense, Denmark.

PloS one
|April 25, 2024
PubMed
概括

一种新的测定方法,MicroSight® MSI,提供了一种快速,客观的方法来检测微卫星不稳定性 (MSI),这对于癌症免疫疗法至关重要. 这种方法可以准确地识别不匹配的修复缺陷,而不需要非瘤组织,简化治疗决策.

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相关概念视频

Mass Spectrum: Interpretation01:24

Mass Spectrum: Interpretation

An unknown compound can be established by identifying the molecular ion peak in the mass spectrum. The molecular ion peak is often weak or absent due to the predominance of fragmentation in high-energy electron beams. In such cases, a soft-energy electron beam can be used to scan the spectrum to enhance the intensity of the molecular ion peak. Additionally, chemical ionization, field ionization, and desorption ionization spectra are used to obtain a relatively intense molecular ion peak.To...
Mass Analyzers: Overview01:13

Mass Analyzers: Overview

The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...