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Updated: Jun 27, 2025

Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets
08:08

Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets

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肺血栓性肺高血压是使用抗血栓剂和肺血管扩张剂治疗来管理的

Rina Horikawa1,2, Ryohei Suzuki1, Yunosuke Yuchi1

  • 1Laboratory of Veterinary Internal Medicine, School of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Tokyo, Japan.

Journal of veterinary internal medicine
|April 25, 2024
PubMed
概括

一名患有严重呼吸困扰和疑似肺血栓的莱昂伯格患者,尽管初始治疗,但症状持续. 与蒙特普拉斯的纤维解药疗法导致肺高血压和呼吸功能显著改善.

关键词:
贝拉普罗斯特酸盐与对比度增强的计算机断层扫描.蒙特普莱斯的地方心肌肌肉菌株的压力肺血管阻力 肺血管阻力斑点跟踪回声心脏图谱 斑点跟踪回声心脏图谱

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The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats07:29

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Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
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Receptor tyrosine kinase inhibitors (TKIs) and calcium channel blockers (CCBs) are two critical categories of drugs employed in the treatment of pulmonary artery hypertension (PAH). PAH is a disease that causes high blood pressure in the pulmonary arteries, resulting in chest pain, fatigue, and shortness of breath.
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