妊娠期PBDE度,持续的外部化和青少年的新兴内部化行为:HOME研究
Kim M Cecil1, Yingying Xu2, Aimin Chen3
1Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Department of Radiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Environmental research
|April 25, 2024
概括
孕期暴露于多二乙烯 (PBDE) 与青少年的行为问题有关,包括注意力不集中和外部化问题. 这些关联从童年持续到青春期早期,特别是在男性中.
科学领域:
- 环境健康 环境健康
- 发展心理学 发展心理学
- 毒理学 毒理学 毒理学
背景情况:
- 聚二乙烯 (PBDE) 是消费品中发现的阻燃剂.
- 产前PBDE暴露与儿童的行为问题有关.
- 这些关联在青春期持续存在的原因尚不清楚.
研究的目的:
- 评估12岁早期青少年妊娠期PBDE血清度与行为之间的关联.
- 为了确定儿童与PBDE的行为关联是否持续到青春期.
主要方法:
- 在怀孕期间测量了母亲血清PBDE度.
- 青少年的行为在12岁时被评估,使用自我和照顾者报告 (BASC-3).
- 用多变量线性回归和引导来分析关联,用性别分层分析来修改效果.
主要成果:
- 孕期PBDE与青少年报告的注意力不集中,过度活跃,内化问题,功能障碍和情绪症状有关.
- PBDE与护理人员报告的外部化问题和行为症状有关.
- 在男性中观察到妊娠期PBDE和外部化行为,特别是执行功能之间的更强的关联.
结论:
- 产前PBDE暴露与青春期早期自我报告的内化和外化行为有关.
- 在童年时期发现的外部化行为持续到青春期,与妊娠期PBDE有关.
- 护理人员不太可能在产前暴露于PBDE的青少年中识别内化行为.
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