相关实验视频

Updated: Jun 27, 2025

Measuring Enzymatic Activity of Neurodevelopmental Disorder-Associated Deubiquitylating Enzymes via an In Vitro Ubiquitin Chain Cleavage Assay
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Measuring Enzymatic Activity of Neurodevelopmental Disorder-Associated Deubiquitylating Enzymes via an In Vitro Ubiquitin Chain Cleavage Assay

Published on: September 27, 2024

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在OTUB1二基因酶中的热点点微环境驱动其稳定性和聚合性

Sushanta Majumder1, Mitul Srivastava2, Parvez Alam3

  • 1Functional Proteomics Laboratory, Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, India.

The Journal of biological chemistry
|April 25, 2024
PubMed
概括

研究人员在OTUB1蛋白上确定了防止粉样蛋白聚合的关键部位,这是与帕金森病 (PD) 相关的过程. 修改这些位点可以提高稳定性,并提供对蛋白质折叠和PD机制的见解.

关键词:
OTUB1 在线播放帕金森病是帕金森病的一种.没有二维基丁酶.不同类型的聚合聚合.莱维的身体身体.蛋白质聚合蛋白质的聚合物蛋白质错折的疾病 蛋白质错折的疾病

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