坚持生活必需品8与延迟生物衰老有关:基于人口的横截面研究
Hongyu Chen1, Haoxian Tang2, Xuan Zhang3
1Department of Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
Revista espanola de cardiologia (English ed.)
|April 25, 2024
概括
坚持美国心脏协会的坚持
科学领域:
- 老年学和心血管健康
- 公共卫生与衰老研究 公共卫生与衰老研究
背景情况:
- 人们越来越担心人口老龄化和与年龄有关的疾病.
- 美国心脏协会更新了心血管健康 (CVH) 的生命必需8 (LE8) 框架.
研究的目的:
- 调查遵守LE8分数与延迟生物衰老之间的关联.
- 评估心血管健康对生物衰老标志物的影响.
主要方法:
- 对18261名成年人 (≥20岁) 的分析,使用国家健康和营养检查调查数据 (2005-2010,2015-2018).
- 通过比较生物/表型年龄和使用临床生物标志物的时间年龄来评估生物衰老.
- 回归分析探讨了LE8分数与生物衰老之间的关系.
主要成果:
- 每增加10点的LE8分数与生物年龄下降1.19年,表型年龄下降1.63年相关.
- 与低CVH相比,高CVH与加速衰老 (生物年龄) 的风险降低了90%和风险降低了81% (表型年龄).
- 血糖被确定为延缓衰老的重要因素;LE8在各个子组中始终显示与生物衰老的负相关性.
结论:
- 较高的心血管健康,以LE8得分为标志,与生物衰老风险降低有关.
- 建议在人口统计学上保持较高的LE8水平,以促进健康的衰老和延迟生物衰老.
- 这些发现对以衰老为重点的初级医疗保健策略有重大影响.
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