饮食维生素C和维生素E与大动脉动脉瘤和剖析的风险:基于人口的前性队列研究
Chuan-Rui Zeng1, Jing-Wei Gao1, Mao-Xiong Wu1
1Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China; Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Nutrition, metabolism, and cardiovascular diseases : NMCD
|April 25, 2024
概括
摄入维生素C (VC) 和维生素E (VE) 的饮食摄入量较高,与大动脉动脉瘤和剖析 (AAD) 的风险较低有关. 这表明,以VC和VE为重点的饮食策略可能会降低AAD发病率,特别是在高风险人群中.
科学领域:
- 营养流行病学 营养流行病学
- 心血管疾病研究研究
- 公共卫生 营养 公共卫生 营养
背景情况:
- 饮食维生素C (VC) 和维生素E (VE) 摄入量与大动脉动脉瘤和解剖 (AAD) 风险之间的关系尚未得到充分证实.
- 了解这些关联对于制定预防性饮食策略至关重要.
研究的目的:
- 为了前性地研究饮食中VC和VE摄入量与发生大动脉动脉瘤和解剖 (AAD) 的风险之间的关联.
主要方法:
- 分析了来自139,477名英国生物库参与者的数据.
- 通过24小时回忆问卷评估的饮食摄入量.
- 考克斯比例回归模型用于分析与事件AAD的关联,平均随访时间为12.5年.
主要成果:
- 饮食中VC和VE摄入量较高的四分位数与发生的AAD相反相关.
- 将最高四分位数与最低四分位数进行比较,VC的调整HR为0.77 (95%CI,0.63-0.93) 和VE为0.70 (95%CI,0.57-0.87).
- 这些反向关联在老年人,吸烟者和高血压或高脂血症患者中更为明显.
结论:
- 增加维生素C和维生素E的饮食摄入量与大动脉动脉瘤和剖析的风险降低有关.
- 侧重于VC和VE摄入量的饮食调整对于降低AAD发病率至关重要,特别是在高风险人群中.
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