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Updated: Jun 27, 2025

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低ACADM表达预测了清细胞细胞癌的不良预后和抑制性瘤微环境

Libin Zhou1,2, Min Yin1,2, Fei Guo3

  • 1Department of Urology, The Affiliated Lihuili Hospital, Ningbo University, Ningbo, China.

Scientific reports
|April 25, 2024
PubMed
概括

下调的中链乙基-CoA脱酶 (ACADM) 与清细胞细胞癌 (ccRCC) 的预后不佳有关. 较低的ACADM水平也预测了ccRCC患者免疫治疗反应的减少.

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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