影响多发性硬化症患者对疲劳感知的临床变量:使用FSIQ-RMS进行的横截面研究
Giovanni Sellitto1,2, Ilaria Ruotolo3,4, Antonio Ianniello3
1MS Center, S. Andrea Hospital, Sapienza University, Rome, Italy. giovanni.sellitto@uniroma1.it.
BMC neurology
|April 25, 2024
概括
身体疲劳显著影响多发性硬化症患者. 较低的BMI和较高的残疾与疲劳增加相关,而物理治疗和工作状态显示改善.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 患者报告的结果
背景情况:
- 身体疲劳是多发性硬化症 (PwMS) 患者的主要致残症状.
- 诸如BMI,残疾 (EDSS) 和生活方式等因素会影响疲劳.
- 疲劳症状和影响问卷-复发性多发性硬化症 (FSIQ-RMS) 测量疲劳的影响.
研究的目的:
- 为了评估疲劳对PwMS的影响,使用FSIQ-RMS.
- 在PwMS中识别与疲劳严重程度相关的因素.
主要方法:
- 在2021年5月至7月期间,有178家PwMS注册.
- 使用经过验证的意大利FSIQ-RMS来评估疲劳.
- 收集了包括BMI和EDSS在内的临床和人口统计数据.
主要成果:
- FSIQ-RMS得分与EDSS有显著的相关性 (p<0.01).
- 较低的BMI组报告了更高的疲劳得分 (p<0.01).
- 物理治疗 (Ph) 和积极工作状态 (Ws) 与疲劳改善有关 (分别p<0.05和p<0.01).
结论:
- 体重不足和高度残疾与PwMS的显著疲劳有关.
- 物理治疗和保持活跃的工作与减少疲劳有积极的相关性.
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