美国广播公司的传送器是几十亿年前的麦克斯韦尔恶魔
Solange Flatt1, Daniel Maria Busiello1,2, Stefano Zamuner1
1Institute of Physics, School of Basic Sciences, École Polytechnique Fédérale de Lausanne-EPFL, Lausanne, 1015 Switzerland.
概括
携带ATP结合盒 (ABC) 运输器作为分子机器,使用ATP进出口物质. 我们的模型显示这些传送器是自主的麦克斯韦恶魔,利用信息来挑战热力学平衡.
科学领域:
- 生物化学 生物化学
- 分子生物学分子生物学
- 热力学是一种热力学.
背景情况:
- ATP结合盒 (ABC) 输送器是无处不在的细胞机器.
- 它们通过ATP水解驱动的介导基质穿越膜的运输.
- 保持度梯度是一个关键功能.
研究的目的:
- 提出ABC传送器模型作为自主麦克斯韦尔恶魔的分子实现.
- 在ABC传送器功能中弥合分子机制和信息理论之间的差距.
主要方法:
- 为ABC传送器开发生物物理和生物化学模型.
- 对模型的分析,以确定新出现的麦克斯韦尔恶魔特征.
- 将分子特性与信息处理概念联系起来.
主要成果:
- 该模型表明,ABC传送器是自主麦克斯韦尔恶魔的精确分子实现.
- 在这些传送器中,Allostery成为信息处理的关键机制.
- 该框架将分子运算与信息理论概念联系起来.
结论:
- ABC传送器利用信息处理,类似于麦克斯韦恶魔,驱动系统远离平衡.
- 对于信息驱动的运输机制来说,所有监管都是至关重要的.
- 这项工作为ABC传送器功能提供了新的信息理论视角.
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