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相关概念视频

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
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Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
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相关实验视频

Updated: Jun 27, 2025

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
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尾状功能网络会影响随着年龄的增长而发生的大脑结构变化.

Silvia Basaia1, Matteo Zavarella1,2, Giulia Rugarli1,2

  • 1Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.

Brain communications
|April 26, 2024
PubMed
概括
此摘要是机器生成的。

老龄化导致大脑网络发生变化,特别是在中部尾状区域. 这些区域显示出更大的缩和改变的连接性,表明神经退行性疾病的脆弱性.

关键词:
老化的老化 衰老的老化紧紧跟在后面的时间.连接经济学是连接经济学.结构性核磁共振成像 (MRI)腹腔下部的区域 腹腔下部区域

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科学领域:

  • 神经科学是一个神经科学.
  • 衰老研究研究 衰老研究
  • 脑部成像 脑部成像

背景情况:

  • 随着年龄的增长,神经生成的下降与大脑缩有关.
  • 腹腔下区域 (SVZ) 神经元前体细胞可能会影响条纹活动.
  • 与衰老相关的神经发生衰变可能会改变与尾状核相连的脑部区域.

研究的目的:

  • 研究尾状网络的功能组织与老化中的结构性大脑变化之间的关系.
  • 为了在各个年龄组中比较中间和侧尾状网络的功能连接性和缩模式.

主要方法:

  • 在三个年龄组招募了152名受试者:年轻人 (≤35岁),中年 (36-60岁) 和老年人 (≥60岁).
  • 利用逐步的功能连接分析来绘制年轻成年人尾状网络连接的地图.
  • 在所有年龄组使用T1加权MRI图像评估大脑缩.

主要成果:

  • 中年和老年人表现出从尾状体的功能连接性下降,特别是在额头,顶部,部和部区域.
  • 与年轻人相比,老年人表现出这些叶片的连接性增加,但在特定的头顶和皮下区域的连接性下降.
  • 与侧尾连接区域相比,中尾连接区域在老年人中表现出较大的缩.

结论:

  • 与中间尾状连接的大脑区域比与侧尾状连接的大脑区域更容易受到与年龄相关的缩和网络改变的影响.
  • 靠近腹腔下区域可能有助于观察到中部尾状网络的脆弱性.
  • 逐步功能连接分析是了解神经退行衰老中与SVZ相关的网络中断的一个有价值的工具.