关于肥胖与维生素C需求之间的关系的系统化审查
Julia K Bird1, Edith Jm Feskens1, Alida Melse-Boonstra1
1Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, the Netherlands.
肥胖与较低的维生素C状态有关,可能是由于摄入量减少或身体成分改变. 需要进一步的研究来确认肥胖患者是否有增加的维生素C需求.
科学领域:
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 全球肥胖率正在上升,影响健康和营养需求.
- 体重影响维生素C的需求,目前根据健康体重的个体进行缩放.
- 肥胖对维生素C需求的影响仍然是研究领域.
研究的目的:
- 审查有关肥胖和维生素C状态之间的关系的现有文献.
- 确定将肥胖与维生素C水平变化联系在一起的潜在机制.
- 评估肥胖是否需要增加维生素C的摄入量.
主要方法:
- 进行了一次系统的文献综述.
- 分析了观察和干预研究,检查维生素C与体重相关的状况.
- 通过扫描文献来探索潜在的生物机制.
主要成果:
- 许多观察研究表明,超重和肥胖个体的维生素C水平较低.
- 对干预研究的重新分析表明,即使服用相应剂量的维生素C,肥胖个体的维生素C水平也较低.
- 建议的机制包括改变维生素C的分布,稀释,代谢变化和肠道失调.
结论:
- 有证据表明,超重或肥胖的人的维生素C水平较低.
- 较低的维生素C摄入量可能导致这种观察到的差异.
- 建议进行进一步的药理动力学和耗尽-补充研究,以澄清肥胖症中维生素C的需求.
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