营养状况及其与血液透析患者COVID-19预后的关系
Paz Andrea Bersano-Reyes1, Gema Nieto1, Alicia Cana-Poyatos2
1Department of Food Technology, Food Science, and Nutrition. Universidad de Murcia.
Nutricion hospitalaria
|April 26, 2024
概括
慢性血液透析患者的体重指数和体脂较高,但甘油三和铁素较低,面临COVID-19死亡率增加. 营养状况显著影响这个脆弱群体的结果.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 传染性疾病 传染性疾病
- 营养科学 营养科学
背景情况:
- 患有慢性血液透析 (HD) 的患者因伴随疾病,年龄和免疫功能障碍而面临更高的严重COVID-19风险.
- 营养状况是影响慢性病患者结果的关键因素.
研究的目的:
- 研究慢性HD患者的营养特征.
- 确定这个人群中营养状况和COVID-19预后之间的关联.
主要方法:
- 对189名被诊断患有COVID-19的慢性HD患者进行了回顾性观察性研究.
- 对人口,临床和营养参数的分析,包括体重指数 (BMI),体脂指数 (FTI),甘油三和费里丁.
- 已故和幸存的患者之间的营养标志物的比较.
主要成果:
- 在更高的BMI和FTI和增加的COVID-19死亡率 (p <0.05) 之间发现了显著的关联.
- 较低的甘油和费里丁基线水平与较高的死亡率显著相关 (p < 0.05).
- 在幸存者和非幸存者之间观察到甘油三和费里水平的显著差异.
结论:
- 较高的身体质量指数和体脂含量与慢性HD患者的COVID-19死亡率增加有关.
- 较低的基线甘油三和费里丁水平与这个队列中的COVID-19预后更差有关.
- 最初的营养状况在血液透析患者中SARS-CoV-2感染的结果中起着重要作用.
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